Cryo-electron tomography is a well known technique used for the evaluation of biological specimens. Structural details are imaged in three dimensions in a transmission electron microscope at cryogenic temperatures to reveal information from specimens. With advancements in energy dispersive X-ray spectroscopy and innovations in TEM specimen holder technology, three-dimensional elemental composition information is readily achieved. Fischione Instruments’ advanced specimen holder technology enables tomography at high tilt angles in narrow-gap pole pieces for both the life and the physical sciences.
The beryllium holder tip and clamp minimize X-ray interference for elemental and composition analyses. For use with Thermo Fisher Scientific transmission electron microscopes (TEM), including those having Ultra-X detectors.
The Model 2553 Analytical Cryo Transfer Tomography Holder is available for Thermo Fisher Scientific microscopes.